Cynomolgus BAFFR/TNFRSF13C Protein (BAF-CM10R)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Activity: Immobilized Cynomolgus BAFFR, His Tag at 1ug/ml (100ul/Well) on plate.Dose response curve for Anti-BAFFR Antibody, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Ser7-Ala71

Catalog: BAF-CM10R

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Product Description Recombinant Cynomolgus BAFFR/TNFRSF13C Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser7-Ala71.

Product Background

BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA / TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.

Product Category

Recombinant Protein

Target

BAFFR/TNFRSF13C
Synonyms CD268; BAFFR; BR3; TNFRSF13C; BROMIX; CVID4; prolixin

Gene/Protein ID

XP_001101623.2

Species

Cynomolgus

Exact Sequence

Ser7-Ala71
Molecular Weight The protein has a predicted MW of 7.7 kDa. Due to glycosylation, the protein migrates to 13-25 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Cynomolgus BAFFR, His Tag at 1ug/ml (100ul/Well) on plate.Dose response curve for Anti-BAFFR Antibody, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Cynomolgus BAFFR, His Tag at 1ug/ml (100ul/Well) on plate.Dose response curve for Anti-BAFFR Antibody, hFc Tag with the EC50 of 3.6ng/ml determined by ELISA.
Immobilized Human BAFF (Trimer) , hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus BAFFR, His Tag with the EC50 of 7.4ng/ml determined by ELISA (QC Test).
Cynomolgus BAFFR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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