Cynomolgus BCAM Protein (BCA-CM10M)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Glu32-Gly548

Catalog: BCA-CM10M

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Product Description Recombinant Cynomolgus BCAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu32-Gly548.

Product Background

 Lutheran/basal cell adhesion molecule (Lu/BCAM) is a transmembrane adhesion molecule expressed by erythrocytes and endothelial cells that can interact with the extracellular matrix protein laminin-α5. In sickle cell disease, Lu/BCAM is thought to contribute to adhesion of sickle erythrocytes to the vascular wall, especially during vaso-occlusive crises.

Product Category

 Recombinant Protein

Target

 BCAM

Gene/Protein ID

 A0A7N9CA99

Species

 Cynomolgus

Exact Sequence

 Glu32-Gly548
Molecular Weight The protein has a predicted MW of 57.42 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

Product Tag

 C-His

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Cynomolgus BCAM is greater than 95% as determined by SEC-HPLC.
Cynomolgus BCAM on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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