Cynomolgus BDCA-2 Protein (BCA-CM202)
Cynomolgus BDCA-2 Protein (BCA-CM202)
Cynomolgus BDCA-2 Protein (BCA-CM202)
  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus BDCA-2, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-BDCA-2 Antibody, hFc Tag with the EC50 of 15.5ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Tyr48-Ile212
Catalog #BCA-CM202
Regular price $315.00
/
Size

Order now, ships by:

Product Description

Recombinant Cynomolgus BDCA-2 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Tyr48-Ile212.

Product Background

BDCA-2 is a novel type II C-type lectin specifically expressed by plasmacytoid dendritic cells (PDCs) that can internalize antigen for presentation to T cells. Furthermore, signaling via BDCA-2 may play a role in switching from interferon (IFN)-α/β-controlled to interleukin (IL)-12-controlled immune response pathways, as triggering of BDCA-2 potently inhibits secretion of IFN-α/β by PDCs and thereby promotes IL-12 p70 production in PDCs and other cells.

Product Category

Recombinant Protein / Antibody discovery

Protein

BDCA-2

Synonyms

BDCA-2; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; CLEC4C; CD303;

Accession

Species

Cynomolgus

Biotinylated

no

Amino Acid Range

Tyr48-Ile212

Molecular Weight

The protein has a predicted MW of 44.99 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Cynomolgus BDCA-2, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-BDCA-2 Antibody, hFc Tag with the EC50 of 15.5ng/ml determined by ELISA. See testing image for detail.

Product Tag

N-hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Cynomolgus BDCA-2, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-BDCA-2 Antibody, hFc Tag with the EC50 of 15.5ng/ml determined by ELISA. Immobilized Cynomolgus BDCA-2, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-BDCA-2 Antibody, hFc Tag with the EC50 of 15.5ng/ml determined by ELISA.
Cynomolgus BDCA-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus BDCA-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus BDCA-2 is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus BDCA-2 is greater than 95% as determined by SEC-HPLC.

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Recently viewed