Name: Cynomolgus BDCA-2 Protein (BCA-CM302)
Brand: KactusBio
SKU: BCA-CM302-100UG
Price: 315.0 USD
Availability: InStock

Express System: HEK293
Product Tag: N-mFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus BDCA-2, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-BDCA-2 Antibody, hFc Tag with the EC50 of 15.1ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Tyr48-Ile212

Catalog #BCA-CM302

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus BDCA-2 Protein is expressed from HEK293 with mFc (IgG2a) tag at the N-Terminus.It contains Tyr48-Ile212.
Product Background	BDCA-2, BDCA-3, and BDCA-4. In blood, BDCA-2 and BDCA-4 are expressed on CD11c(-) CD123(bright) plasmacytoid dendritic cells, whereas BDCA-3 is expressed on small population of CD11c() CD123(-) dendritic cells. All three Ags are not detectable on a third blood dendritic cell population, which is CD1c() CD11c(bright) CD123(dim), or on any other cells in blood.BDCA-2 is completely down-regulated on plasmacytoid CD11c(-) CD123(bright) dendritic cells, BDCA-2 is rapidly internalized at 37 degrees C after mAb labeling.
Product Category	Recombinant Protein / Antibody discovery

Protein	BDCA-2
Synonyms	BDCA-2; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; CLEC4C; CD303; CD303; DLEC;
Accession	A0A2K5UWP4
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Tyr48-Ile212
Molecular Weight	The protein has a predicted MW of 46.00 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus BDCA-2, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-BDCA-2 Antibody, hFc Tag with the EC50 of 15.1ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	N-mFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus BDCA-2, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-BDCA-2 Antibody, hFc Tag with the EC50 of 15.1ng/ml determined by ELISA (QC Test).
	Cynomolgus BDCA-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus BDCA-2 is greater than 95% as determined by SEC-HPLC.