Product Description |
Recombinant Cynomolgus BSPII Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe17-Gln318. |
Product Background |
IBSP (Integrin Binding Sialoprotein) is a Protein Coding gene. Diseases associated with IBSP include Fibrous Dysplasia and Chondromalacia. Among its related pathways are Degradation of the extracellular matrix and Cytoskeletal Signaling.The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
BSPII |
Synonyms |
BNSP; BSP 2; BSP II; BSP; BSP-II; IBSP; SP II; SPII; SP-II |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
no |
Amino Acid Range |
Phe17-Gln318 |
Molecular Weight |
The protein has a predicted MW of 34.63 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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Cynomolgus BSPII on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Cynomolgus BSPII is greater than 95% as determined by SEC-HPLC. |
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