Name: Cynomolgus c-MPL/Thrombopoietin R Protein (MPL-CM101)
Brand: KactusBio
SKU: MPL-CM101-100UG
Price: 315.0 USD
Availability: InStock

Cynomolgus c-MPL/Thrombopoietin R Protein (MPL-CM101)

Immobilized Cynomolgus c-MPL, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-C-MPL Antibody, hFc Tag with the EC50 of 2.3ng/ml determined by ELISA.

Cynomolgus c-MPL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Cynomolgus c-MPL, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-C-MPL Antibody, hFc Tag with the EC50 of 2.3ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gln22-Thr489

Catalog #MPL-CM101

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus c-MPL/Thrombopoietin R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln22-Thr489.
Product Background	The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for myeloproliferative leukemia virus) has transduced a truncated and constitutively activated form of the c-mpl receptor chain. High levels of c-mpl expression were detected in 45% of acute myeloid leukemia (AML). No correlation was found between c-mpl expression and the French-American-British classification subtype of AML.
Product Category	Recombinant Protein / Antibody discovery

Protein	c-MPL/Thrombopoietin R
Synonyms	TPO-R; CD110; MPL; c-Mpl; MPLV; K12
Accession	A0A2K5UGC7
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gln22-Thr489
Molecular Weight	The protein has a predicted MW of 53.48 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus c-MPL, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-C-MPL Antibody, hFc Tag with the EC50 of 2.3ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl, 3mM DTT, 10% Glycerol (pH 7.5).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus c-MPL, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-C-MPL Antibody, hFc Tag with the EC50 of 2.3ng/ml determined by ELISA.
	Cynomolgus c-MPL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.