Cynomolgus CADM3 Protein (CDM-CM103)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Asn23-Thr326

Catalog: CDM-CM103

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Product Description Recombinant Cynomolgus CADM3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asn23-Thr326.

Product Background

Cell adhesion molecules belonging to the Cadm family, and in particular Cadm3 (axonal) and its heterophilic binding partner Cadm4 (Schwann cell), mediate these interactions along the internode.over-expressing Cadm3 on the surface of DRG neuron axons results in an almost complete inability by Schwann cells to form myelin segments. Axons of superior cervical ganglion (SCG) neurons, which do not normally support the formation of myelin segments by Schwann cells, express higher levels of Cadm3 compared to DRG neurons.

Product Category

Recombinant Protein

Target

CADM3

Gene/Protein ID

A0A2K5UJL5

Species

Cynomolgus

Exact Sequence

Asn23-Thr326
Molecular Weight The protein has a predicted MW of 34.46 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Cynomolgus CADM3 is greater than 95% as determined by SEC-HPLC.
Cynomolgus CADM3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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