Cynomolgus CADM3 Protein (CDM-CM103)
Cynomolgus CADM3 Protein (CDM-CM103)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Asn23-Thr326
Catalog #CDM-CM103
Regular price $315.00
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Product Description
Recombinant Cynomolgus CADM3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asn23-Thr326.
Product Background
Cell adhesion molecules belonging to the Cadm family, and in particular Cadm3 (axonal) and its heterophilic binding partner Cadm4 (Schwann cell), mediate these interactions along the internode.over-expressing Cadm3 on the surface of DRG neuron axons results in an almost complete inability by Schwann cells to form myelin segments. Axons of superior cervical ganglion (SCG) neurons, which do not normally support the formation of myelin segments by Schwann cells, express higher levels of Cadm3 compared to DRG neurons.
Product Category
Recombinant Protein
Target
CADM3
Synonyms
IgSF4B; NECL-1; SynCAM3; GSF4B; NECL1; TSLL1; CADM3; BIgR; IGSF4B; member 4B; TSLC1-like 1
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Asn23-Thr326
Molecular Weight
The protein has a predicted MW of 34.46 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Cynomolgus CADM3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus CADM3 is greater than 95% as determined by SEC-HPLC.

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