Cynomolgus CCL24 Protein (CCL-CM124)
Catalog: CCL-CM124
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Product Description | Recombinant Cynomolgus CCL24 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains His19-His119. |
Product Background |
C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fibrosis. It was found to be significantly expressed in patients with non-alcoholic steatohepatitis, in whom it regulates profibrotic processes in the liver. |
Product Category |
Recombinant Protein |
Target |
CCL24 |
Accession | |
Species |
Cynomolgus |
Amino Acid Range |
His19-His119 |
Molecular Weight | The protein has a predicted MW of 12.36 kDa. Due to glycosylation, the protein migrates to 23-38 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Cynomolgus CCL24, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCL24 Antibody, hFc Tag with the EC50 of 18.7ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
N-His |
Express System |
HEK293 |
Purity | > 90% as determined by Tris-Bis PAGE;> 90% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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