Name: Cynomolgus CCR8 Protein (CCR-CM308)
Brand: KactusBio
SKU: CCR-CM308-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-mFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus CCR8, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR8 Antibody, hFc Tag with the EC50 of 6.1ng/ml determined by ELISA. The affinity constant of 0.27 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Met1-Lys35

Catalog #CCR-CM308

Size

100UG

500UG

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Cynomolgus CCR8 Protein (CCR-CM308) Summary

Product Description	Recombinant Cynomolgus CCR8 Protein is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Met1-Lys35.
Product Background	CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Cynomolgus CCR8 Protein (CCR-CM308) Specifications/Details

Protein	CCR8
Synonyms	CCR-8; CMKBRL2; CKR-L1; GPR-CY6; GPRCY6; TER1; CCR8; CKRL1; CMKBR8; CD198; ChemR1; CKR-L1; CY6; TER-1; CDw198
Accession	XP_015300839.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Met1-Lys35
Molecular Weight	The protein has a predicted MW of 29.73 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus CCR8, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR8 Antibody, hFc Tag with the EC50 of 6.1ng/ml determined by ELISA. The affinity constant of 0.27 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-mFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Anti-CCR8 Antibody, hFc Tag captured on CM5 Chip via Anti-Human Fc IgG Antibody can bind Cynomolgus CCR8, mFc Tag with an affinity constant of 0.27 uM as determined in SPR assay (Biacore T200).
	Immobilized Cynomolgus CCR8, mFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCR8 Antibody, hFc Tag with the EC50 of 6.1ng/ml determined by ELISA.
	Cynomolgus CCR8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus CCR8 is greater than 95% as determined by SEC-HPLC.