Cynomolgus CD10/MME Protein (MME-CM110)

  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Asp53-Trp750

Catalog: MME-CM110

$315.00
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Product Description Recombinant Cynomolgus CD10/MME Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Asp53-Trp750.

Product Background

CD10 is an endopeptidase that degrades various bioactive peptides in the extracellular matrix. In addition to enzymatic degradation, it affects multiple intracellular signal transduction pathways. CD10 expression has been extensively studied in human epithelial cancers of numerous organs and sites. CD10 expression pattern depended on the histotypes of thyroid lesions. When possible metastatic tumours and non-epithelial tumours are excluded, high CD10 expression may be useful in determining whether a primary thyroid carcinoma includes an anaplastic component.

Product Category

Recombinant Protein

Target

CD10/MME
Accession

Species

Cynomolgus

Amino Acid Range

Asp53-Trp750
Molecular Weight The protein has a predicted MW of 80.69 kDa. Due to glycosylation, the protein migrates to 81-110 kDa based on Tris-Bis PAGE result.

Product Tag

N-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPPGFSAFK (Dnp) -OH. The specific activity is > 1200 pmoles/min/ug.
The purity of Cynomolgus CD10 is greater than 95% as determined by SEC-HPLC.
Cynomolgus CD10 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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