Cynomolgus CD30/TNFRSF8 Protein (CD3-CM130)
Cynomolgus CD30/TNFRSF8 Protein (CD3-CM130)
Cynomolgus CD30/TNFRSF8 Protein (CD3-CM130)
Cynomolgus CD30/TNFRSF8 Protein (CD3-CM130)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus CD30, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CD30 Antibody, hFc Tag with the EC50 of 6.0ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Ala27-Pro394
Catalog #CD3-CM130
Regular price $315.00
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Product Description
Recombinant Cynomolgus CD30/TNFRSF8 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala27-Pro394.
Product Background
The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions. CD30 expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs).
Product Category
Recombinant Protein
Target
CD30/TNFRSF8
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Ala27-Pro394
Molecular Weight
The protein has a predicted MW of 39.86 kDa. Due to glycosylation, the protein migrates to 75-105 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Cynomolgus CD30, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CD30 Antibody, hFc Tag with the EC50 of 6.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Cynomolgus CD30, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CD30 Antibody, hFc Tag with the EC50 of 6.0ng/ml determined by ELISA (QC Test).
Cynomolgus CD30 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus CD30 is greater than 95% as determined by SEC-HPLC.

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