Cynomolgus DLL3 Protein (DLL-CM113)
Catalog: DLL-CM113
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Product Description | Recombinant Cynomolgus DLL3 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala27-Arg488. |
Product Background |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). |
Product Category |
Recombinant Protein |
Target |
DLL3 |
Gene/Protein ID |
A0A2K5WSR1 |
Species |
Cynomolgus |
Exact Sequence |
Ala27-Arg488 |
Molecular Weight | The protein has a predicted MW of 49.21 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Cynomolgus DLL3, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22 um filtered solution in 20mM Tris, 200mM NaCl, 200mM L-arginine (pH 8.5). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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