Cynomolgus CD44 Protein (CDX-CM144)
Cynomolgus CD44 Protein (CDX-CM144)
Cynomolgus CD44 Protein (CDX-CM144)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus CD44, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD44 Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Gln21-Pro220 & Gln387-Ala428
Catalog #CDX-CM144
Regular price $315.00
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Product Description
Recombinant Cynomolgus CD44 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln21-Pro220 & Gln387-Ala428.
Product Background
CD44 is a hyaluronan binding cell surface signal transducing receptor that influences motility, cell survival and proliferation as well as the formation of tumor microenvironment. CD44 contains two variable regions encoded by variable exons. Alternative splicing, which is often deregulated in cancer, can produce various isoforms of CD44 with properties that may have different tissue specific effects and therefore even diverse effects on cancer progression
Product Category
Recombinant Protein
Target
CD44
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Gln21-Pro220 & Gln387-Ala428
Molecular Weight
The protein has a predicted MW of 27.77 kDa. Due to glycosylation, the protein migrates to 45-70 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Cynomolgus CD44, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD44 Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Cynomolgus CD44, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD44 Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA (QC Test).
Cynomolgus CD44 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus CD44 is greater than 95% as determined by SEC-HPLC.

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