Name: Cynomolgus CD83 Protein (CD8-CM183)
Brand: KactusBio
SKU: CD8-CM183-100UG
Price: 315.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus CD83, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti- CD83 Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Thr20-Glu147

Catalog #CD8-CM183

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus CD83 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr20-Glu147.
Product Background	CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated immune cells, although it is most highly and stably expressed by mature dendritic cells (DC). While CD83 is emerging as a promising immune modulator with therapeutic potential, some important aspects such as its ligand/s, intracellular signaling pathways and modulators of its expression are unclear.
Product Category	Recombinant Protein / Antibody discovery

Protein	CD83
Synonyms	CD83; HB15; BL11; CD83 molecule
Accession	A0A2K5US85
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Thr20-Glu147
Molecular Weight	The protein has a predicted MW of 15.43 kDa. Due to glycosylation, the protein migrates to 25-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus CD83, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti- CD83 Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus CD83, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti- CD83 Antibody, hFc Tag with the EC50 of 2.0ng/ml determined by ELISA.
	Cynomolgus CD83 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus CD83 is greater than 95% as determined by SEC-HPLC.