Cynomolgus CD96/TACTILE Protein (CD9-CM196)
Cynomolgus CD96/TACTILE Protein (CD9-CM196)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus CD96, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD96 Antibody, hFc Tag with the EC50 of 0.93ug/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Val22-Gly502
Catalog #CD9-CM196
Regular price $315.00
/
Size

Order now, ships by:

Product Description
Recombinant Cynomolgus CD96/TACTILE Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val22-Gly502.
Product Background
The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development.
Product Category
Recombinant Protein
Target
CD96/TACTILE
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Val22-Gly502
Molecular Weight
The protein has a predicted MW of 54.27 kDa. Due to glycosylation, the protein migrates to 80-130 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Cynomolgus CD96, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD96 Antibody, hFc Tag with the EC50 of 0.93ug/ml determined by ELISA. See testing image for detail.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Cynomolgus CD96, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD96 Antibody, hFc Tag with the EC50 of 0.93ug/ml determined by ELISA.
Cynomolgus CD96 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus CD96 is greater than 95% as determined by SEC-HPLC.

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Recently viewed