Cynomolgus CD98 Protein (CD9-CM198)

  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus CD98, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD98 Antibody, hFc Tag with the EC50 of 30.8ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Arg175-Ala599

Catalog: CD9-CM198

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Product Description Recombinant Cynomolgus CD98 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Arg175-Ala599.

Product Background

The type II transmembrane protein CD98, best known as the heavy chain of the heterodimeric amino acid transporters (HAT), is required for the surface expression and basolateral localization of this transporter complex in polarized epithelial cells. CD98 also interacts with beta1 integrins resulting in an increase in their affinity for ligand. In this study we explored the role of the transmembrane and cytoplasmic domains of CD98 on integrin-dependent cell adhesion and migration in polarized renal epithelial cells.

Product Category

Recombinant Protein

Target

CD98

Gene/Protein ID

XP_045227941.1

Species

Cynomolgus

Exact Sequence

Arg175-Ala599
Molecular Weight The protein has a predicted MW of 48.02 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Cynomolgus CD98, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD98 Antibody, hFc Tag with the EC50 of 30.8ng/ml determined by ELISA. See testing image for detail.

Product Tag

N-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Cynomolgus CD98, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD98 Antibody, hFc Tag with the EC50 of 30.8ng/ml determined by ELISA.
The purity of Cynomolgus CD98 is greater than 95% as determined by SEC-HPLC.
Cynomolgus CD98 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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