Cynomolgus CD98 Protein (CD9-CM198)

  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus CD98, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD98 Antibody, hFc Tag with the EC50 of 16.8ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Arg175-Ala599

Catalog: CD9-CM198

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Product Description Recombinant Cynomolgus CD98 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Arg175-Ala599.

Product Background

The type II transmembrane protein CD98, best known as the heavy chain of the heterodimeric amino acid transporters (HAT), is required for the surface expression and basolateral localization of this transporter complex in polarized epithelial cells. CD98 also interacts with beta1 integrins resulting in an increase in their affinity for ligand. In this study we explored the role of the transmembrane and cytoplasmic domains of CD98 on integrin-dependent cell adhesion and migration in polarized renal epithelial cells.

Product Category

Recombinant Protein

Target

CD98
Accession

Species

Cynomolgus

Exact Sequence

Arg175-Ala599
Molecular Weight The protein has a predicted MW of 48.02 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Cynomolgus CD98, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD98 Antibody, hFc Tag with the EC50 of 16.8ng/ml determined by ELISA. See testing image for detail.

Product Tag

N-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Cynomolgus CD98, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD98 Antibody, hFc Tag with the EC50 of 16.8ng/ml determined by ELISA.
The purity of Cynomolgus CD98 is greater than 95% as determined by SEC-HPLC.
Cynomolgus CD98 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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