Cynomolgus CDCP1 Protein (CDC-CM102)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus CDCP1, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CDCP1 Antibody, hFc Tag with the EC50 of 12.2ng/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Phe30-Thr667

Catalog: CDC-CM102

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Product Description Recombinant Cynomolgus CDCP1 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Phe30-Thr667.

Product Background

Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.

Product Category

Recombinant Protein

Target

CDCP1

Gene/Protein ID

XP_005546930.2

Species

Cynomolgus

Exact Sequence

Phe30-Thr667
Molecular Weight The protein has a predicted MW of 73.15 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Cynomolgus CDCP1, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CDCP1 Antibody, hFc Tag with the EC50 of 12.2ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Cynomolgus CDCP1, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CDCP1 Antibody, hFc Tag with the EC50 of 12.2ng/ml determined by ELISA.
The purity of Cynomolgus CDCP1 is greater than 95% as determined by SEC-HPLC.
Cynomolgus CDCP1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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