Cynomolgus Claudin 6 Protein-VLP (CLD-CM006)

Express System: HEK293
Purity: > 95% as determined by HPLC
Activity: Immobilized Cynomolgus Claudin 6 VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 4ng/ml determined by ELISA (QC Test). The affinity constant of 0.85 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Exact Sequence: Met1-Val220

Catalog: CLD-CM006

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Product Description	Recombinant Cynomolgus Claudin 6 Protein-VLP is expressed from HEK293.It contains Met1-Val220.
Product Background	Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively.
Product Category	Recombinant Protein

Target	Claudin 6
Gene/Protein ID	G7Q0B0
Species	Cynomolgus
Exact Sequence	Met1-Val220
Molecular Weight	The target protein has a predicted MW of 24.60 kDa.
Activity	Immobilized Cynomolgus Claudin 6 VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 4ng/ml determined by ELISA (QC Test). The affinity constant of 0.85 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Express System	HEK293
Purity	> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in PBS (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Cynomolgus Claudin 6 VLP immobilized on CM5 Chip can bind Anti-Claudin 6 Antibody with an affinity constant of 0.85 nM as determined in SPR assay (Biacore T200).
	Immobilized Cynomolgus Claudin 6 VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 4ng/ml determined by ELISA (QC Test).
	The purity of Cynomolgus Claudin 6 VLP is greater than 95% as determined by SEC-HPLC.