Cynomolgus CLEC12A/MICL/CLL-1 Protein (CLE-CM12A)

  • Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Exact Sequence: His32-Ala232

Catalog: CLE-CM12A

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Product Description Recombinant Cynomolgus CLEC12A/MICL/CLL-1 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains His32-Ala232.

Product Background

CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML.

Product Category

Recombinant Protein

Target

CLEC12A/MICL/CLL-1
Synonyms MICL; CLL-1; CLEC12A; CLL1; DCAL2; DCAL-2; CD371; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; DCAL-2

Gene/Protein ID

A0A2K5WXQ6

Species

Cynomolgus

Exact Sequence

His32-Ala232
Molecular Weight The protein has a predicted MW of 24.6 kDa. Due to glycosylation, the protein migrates to 38-50 kDa based on Tris-Bis PAGE result.

Product Tag

N-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Cynomolgus CLEC12A on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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