Name: Cynomolgus CRTAM Protein (CRM-CM201)
Brand: KactusBio
SKU: CRM-CM201-100UG
Price: 264.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus CRTAM, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CRTAM Antibody, hFc Tag with the EC50 of 73.9ng/ml determined by ELISA.
Amino Acid Range: Ser18-Gly287

Catalog #CRM-CM201

Size

100UG

500UG

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Cynomolgus CRTAM Protein (CRM-CM201) Summary

Product Description	Recombinant Cynomolgus CRTAM Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Ser18-Gly287.
Product Background	Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Cynomolgus CRTAM Protein (CRM-CM201) Specifications/Details

Protein	CRTAM
Synonyms	CD355 antigen; CD355; CRTAM
Accession	XP_005580021.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Ser18-Gly287
Molecular Weight	The protein has a predicted MW of 56.6 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus CRTAM, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CRTAM Antibody, hFc Tag with the EC50 of 73.9ng/ml determined by ELISA.
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus CRTAM, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-CRTAM Antibody, hFc Tag with the EC50 of 73.9ng/ml determined by ELISA.
	Cynomolgus CRTAM on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus CRTAM is greater than 95% as determined by SEC-HPLC.

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