Cynomolgus CSPG4/MCSP Protein (CSP-CM1P4)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Ser1581-Ser2222

Catalog: CSP-CM1P4

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Product Description Recombinant Cynomolgus CSPG4/MCSP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser1581-Ser2222.

Product Background

The chondroitin sulfate proteoglycan-4 (CSPG4) is a cell surface proteoglycan overexpressed in a huge range of human and canine neoplastic lesions by tumor cells, tumor microenvironment and cancer initiating cells. CSPG4 plays a central role in the oncogenic pathways required for malignant progression and metastatization.

Product Category

Recombinant Protein

Target

CSPG4/MCSP

Gene/Protein ID

A0A2K5UW71

Species

Cynomolgus

Exact Sequence

Ser1581-Ser2222
Molecular Weight The protein has a predicted MW of 69.30 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Cynomolgus CSPG4 is greater than 95% as determined by SEC-HPLC.
Cynomolgus CSPG4 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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