Cynomolgus DR6/TNFRSF21 Protein (DR6-CM101)
Cynomolgus DR6/TNFRSF21 Protein (DR6-CM101)
Cynomolgus DR6/TNFRSF21 Protein (DR6-CM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus DR6, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-DR6 Antibody, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln42-His349
Catalog #DR6-CM101
Regular price $270.00
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Product Description
Recombinant Cynomolgus DR6/TNFRSF21 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln42-His349.
Product Background
beta-amyloid precursor protein (APP) and death receptor 6 (DR6, also known as TNFRSF21) activate a widespread caspase-dependent self-destruction program. DR6 is broadly expressed by developing neurons, and is required for normal cell body death and axonal pruning both in vivo and after trophic-factor deprivation in vitro.DR6 is activated locally by an inactive surface ligand(s) that is released in an active form after trophic-factor deprivation.
Product Category
Recombinant Protein
Target
DR6/TNFRSF21
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Gln42-His349
Molecular Weight
The protein has a predicted MW of 34.50 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Cynomolgus DR6, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-DR6 Antibody, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA. See testing image for detail.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Cynomolgus DR6, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-DR6 Antibody, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA.
Cynomolgus DR6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus DR6 is greater than 95% as determined by SEC-HPLC.

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