Name: Cynomolgus DR6/TNFRSF21 Protein (DR6-CM101)
Brand: KactusBio
SKU: DR6-CM101-100UG
Price: 270.0 USD
Availability: InStock

Cynomolgus DR6/TNFRSF21 Protein (DR6-CM101)

Immobilized Cynomolgus DR6, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-DR6 Antibody, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA.

Cynomolgus DR6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus DR6 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus DR6, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-DR6 Antibody, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gln42-His349

Catalog #DR6-CM101

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus DR6/TNFRSF21 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln42-His349.
Product Background	beta-amyloid precursor protein (APP) and death receptor 6 (DR6, also known as TNFRSF21) activate a widespread caspase-dependent self-destruction program. DR6 is broadly expressed by developing neurons, and is required for normal cell body death and axonal pruning both in vivo and after trophic-factor deprivation in vitro.DR6 is activated locally by an inactive surface ligand(s) that is released in an active form after trophic-factor deprivation.
Product Category	Recombinant Protein / Antibody discovery

Protein	DR6/TNFRSF21
Synonyms	Death receptor 6; CD358; TNFRSF21; DR6; BM-018; MGC31965
Accession	A0A2K5VIJ8
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gln42-His349
Molecular Weight	The protein has a predicted MW of 34.50 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus DR6, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-DR6 Antibody, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus DR6, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-DR6 Antibody, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA.
	Cynomolgus DR6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus DR6 is greater than 95% as determined by SEC-HPLC.