Cynomolgus E-selectin/CD62E Protein (ESE-CM101)
Catalog: ESE-CM101
Order now get it on
| Product Description | Recombinant Cynomolgus E-selectin/CD62E Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Trp22-Pro554. |
Product Background |
E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.E-selectin mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis. |
Product Category |
Recombinant Protein |
Target |
E-Selectin/CD62E |
Gene/Protein ID |
A0A2K5U7H9 |
Species |
Cynomolgus |
Exact Sequence |
Trp22-Pro554 |
| Molecular Weight | The protein has a predicted MW of 59.47 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Cynomolgus E-selectin, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-E-Selectin Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Immobilized Cynomolgus E-selectin, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-E-Selectin Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA. |
|
|
The purity of Cynomolgus E-selectin is greater than 95% as determined by SEC-HPLC. |
|
|
Cynomolgus E-selectin on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
You may also be interested in
View more associated products