Product Description |
Recombinant Cynomolgus EPHA10 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu34-Ala565. |
Product Background |
EphA10 (erythropoietin-producing hepatocellular carcinoma receptor A10) is a catalytically defective receptor protein tyrosine kinase in the ephrin receptor family.EphA10 was elevated and higher in tumor tissues than in normal tissues in some cancer types, including pancreatic cancer.EphA10 silencing reduced the proliferation, migration, and adhesion of MIA PaCa-2 and AsPC-1 pancreatic cancer cells. EphA10 plays a pivotal role in the tumorigenesis of pancreatic epithelial cells and is a novel therapeutic target for pancreatic cancer. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
EPHA10 |
Synonyms |
EphA10; FLJ16103; FLJ33655; MGC43817 |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
no |
Amino Acid Range |
Glu34-Ala565 |
Molecular Weight |
The protein has a predicted MW of 58.56 kDa. Due to glycosylation, the protein migrates to 68-78 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Cynomolgus EPHA10 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Cynomolgus EPHA10 is greater than 95% as determined by SEC-HPLC. |
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