Name: Cynomolgus Fc gamma RIIA/CD32a Protein (CDA-CM132)
Brand: KactusBio
SKU: CDA-CM132-100UG
Price: 264.0 USD
Availability: InStock

Cynomolgus Fc gamma RIIA/CD32a Protein (CDA-CM132)

Cynomolgus Fc gamma RIIA, His Tag captured on CM5 Chip via Anti-his antibody can bind Rituximab with an affinity constant of 4.39 uM as determined in SPR assay (Biacore T200).

Cynomolgus Fc gamma RIIA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus Fc gamma RIIA is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 4.39 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Gln28-Pro208

Catalog #CDA-CM132

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus Fc gamma RIIA/CD32a Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln28-Pro208.
Product Background	The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. The CD64 proteins are high affinity receptors (~10e-8-10e-9 M) capable of binding monomeric IgG, whereas the CD16 and CD32 proteins bind IgG with lower affinities (~10e-6-10e-7 M) only recognizing IgG aggregates surrounding multivalent antigens.
Product Category	Recombinant Protein / Antibody discovery / Fc receptors

Protein	Fc gamma RIIA/CD32a
Synonyms	Fc gamma RIIA; FCG2; FCGR2; FCGR2A; FCGR2A1; FcgRIIA; FCRIIA; fcRII-a; FCG2; CD32A; FcγRIIA; Fc γRIIA; Fcγ RIIA; Fc γ RIIA
Accession	Q8SPW4-1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gln28-Pro208
Molecular Weight	The protein has a predicted MW of 21.3 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 4.39 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Cynomolgus Fc gamma RIIA, His Tag captured on CM5 Chip via Anti-his antibody can bind Rituximab with an affinity constant of 4.39 uM as determined in SPR assay (Biacore T200).
	Cynomolgus Fc gamma RIIA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus Fc gamma RIIA is greater than 95% as determined by SEC-HPLC.