Cynomolgus FcRH5/FcRL5 Protein (FCR-CM101)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Exact Sequence: Gln16-Gly851

Catalog: FCR-CM101

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Product Description Recombinant Cynomolgus FcRH5/FcRL5 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln16-Gly851.

Product Background

FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent.

Product Category

Recombinant Protein

Target

FcRH5/FcRL5
Accession

Species

Cynomolgus

Exact Sequence

Gln16-Gly851
Molecular Weight The protein has a predicted MW of 92.13 kDa. Due to glycosylation, the protein migrates to 100-130 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Cynomolgus FcRH5 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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