Cynomolgus FGL1 Protein (FGL-CM211)
Catalog: FGL-CM211
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Product Description | Recombinant Cynomolgus FGL1 Protein is expressed from HEK293 with hFc at the N-Terminus.It contains Leu23-Ile312. |
Product Background |
Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like protein 2, and clotting factors V, VIII, and XIII.Fibrinogen-like Protein 1 is a major immune inhibitory ligand of LAG-3. |
Product Category |
Recombinant Protein |
Target |
FGL1 |
Synonyms | FGL1; FGL-1; Hepassocin; HP-041; HFREP-1; LFIRE-1; HFREP1; Lag3 ligand |
Accession | |
Species |
Cynomolgus |
Amino Acid Range |
Leu23-Ile312 |
Molecular Weight | The protein has a predicted MW of 55.5 kDa. Due to glycosylation, the protein migrates to 62-68 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Human LAG3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus FGL1, hFc Tag with the EC50 of 54.0ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
N-hFc |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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