Cynomolgus FGL1 Protein (FGL-CM211)

Express System: HEK293
Product Tag: N-hFc
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Human LAG3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus FGL1, hFc Tag with the EC50 of 54.0ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Leu23-Ile312

Catalog: FGL-CM211

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Product Description	Recombinant Cynomolgus FGL1 Protein is expressed from HEK293 with hFc at the N-Terminus.It contains Leu23-Ile312.
Product Background	Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like protein 2, and clotting factors V, VIII, and XIII.Fibrinogen-like Protein 1 is a major immune inhibitory ligand of LAG-3.
Product Category	Recombinant Protein

Target	FGL1
Synonyms	FGL1; FGL-1; Hepassocin; HP-041; HFREP-1; LFIRE-1; HFREP1; Lag3 ligand
Gene/Protein ID	G7N0K6-1
Species	Cynomolgus
Exact Sequence	Leu23-Ile312
Molecular Weight	The protein has a predicted MW of 55.5 kDa. Due to glycosylation, the protein migrates to 62-68 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human LAG3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus FGL1, hFc Tag with the EC50 of 54.0ng/ml determined by ELISA. See testing image for detail.
Product Tag	N-hFc
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human LAG3, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus FGL1, hFc Tag with the EC50 of 54.0ng/ml determined by ELISA.
	The purity of Cynomolgus FGL1 is greater than 95% as determined by SEC-HPLC.
	Cynomolgus FGL1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.