Cynomolgus GITR Ligand/TNFSF18 Protein (FSF-CM118)
Catalog: FSF-CM118
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| Product Description | Recombinant Cynomolgus GITR Ligand/TNFSF18 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln72-Ser199. |
Product Background |
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. |
Product Category |
Recombinant Protein |
Target |
GITR Ligand/TNFSF18 |
Gene/Protein ID |
A0A7N9CM47 |
Species |
Cynomolgus |
Exact Sequence |
Gln72-Ser199 |
| Molecular Weight | The protein has a predicted MW of 15.62 kDa. Due to glycosylation, the protein migrates to 17-27 kDa based on Tris-Bis PAGE result. |
Activity |
The affinity constant of 0.21 uM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Cynomolgus GITR Ligand, His Tag immobilized on CM5 Chip can bind Cynomolgus GITR, His Tag with an affinity constant of 0.21 uM as determined in SPR assay (Biacore T200). |
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The purity of Cynomolgus GITR Ligand is greater than 95% as determined by SEC-HPLC. |
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Cynomolgus GITR Ligand on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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