Cynomolgus GPRC5D VLP (GPR-CM05P) Summary
Product Description |
Recombinant Cynomolgus GPRC5D VLP is expressed from HEK293.; It contains Met1-Cys300 (It may have cross reaction with anti-His antibody). |
Product Background |
G protein–coupled receptor, family C, group 5, member D (GPRC5D) is an orphan receptor that is primarily expressed in plasma cells and hard keratinized tissues, with low expression in normal human tissues. GPRC5D expression is enriched in malignant plasma cells and is associated with markers of high-risk myeloma. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP |
Cynomolgus GPRC5D VLP (GPR-CM05P) Specifications/Details
Protein |
GPRC5D |
Synonyms |
GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
no |
Amino Acid Range |
Met1-Cys300 |
Molecular Weight |
The target protein has a predicted MW of 35.10 kDa. |
Activity |
Immobilized Cynomolgus GPRC5D VLP (100 ul/well) at 5 ug/ml (100 ul/Well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 6.91 ug/ml determined by ELISA. |
Expression System |
HEK293 |
Purity |
> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 300mM L-arginine (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Cynomolgus GPRC5D VLP (100 ul/well) at 5 ug/ml (100 ul/Well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 6.91 ug/ml determined by ELISA. |
|
|
The purity of Cynomolgus GPRC5D VLP is greater than 95% as determined by SEC-HPLC. |
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