Name: Cynomolgus GPVI Protein (GP6-CM101)
Brand: KactusBio
SKU: GP6-CM101-100UG
Price: 315.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Activity: Immobilized Cynomolgus GPVI, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-GPVI Antibody, hFc Tag with the EC50 of 4.9 ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Gln21-Asn251

Catalog #GP6-CM101

Size

100UG

500UG

Order now, ships by:

Product Description	Recombinant Cynomolgus GPVI Protein is expressed from HEK293 with His tag at the C-Terminus; It contains Gln21-Asn251.
Product Background	Although platelets are best known for their role in hemostasis, they are also crucial in development, host defense, inflammation, and tissue repair. Many of these roles are regulated by the immune-like receptors glycoprotein VI (GPVI) and C-type lectin receptor 2 (CLEC-2), which signal through an immunoreceptor tyrosine-based activation motif (ITAM). GPVI is activated by collagen in the subendothelial matrix, by fibrin and fibrinogen in the thrombus, and by a remarkable number of other ligands.
Product Category	Recombinant Protein / Antibody discovery

Protein	GPVI
Synonyms	GPVI; Gp6; Glycoprotein 6; MGC138168
Accession	XP_005590417.2
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gln21-Asn251
Molecular Weight	The protein has a predicted MW of 26.42 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus GPVI, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-GPVI Antibody, hFc Tag with the EC50 of 4.9 ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus GPVI, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-GPVI Antibody, hFc Tag with the EC50 of 4.9 ng/ml determined by ELISA (QC Test).
	Cynomolgus GPVI on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus GPVI is greater than 95% as determined by SEC-HPLC.