• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus GPVI, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-GPVI Antibody, hFc Tag with the EC50 of 4.9 ng/ml determined by ELISA (QC Test).
  • Amino Acid Range: Gln21-Asn251
Catalog #GP6-CM101
Price
Regular price $34650
Regular price Sale price $34650
/
Size
Avantor VWR Fisher Scientific

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Cynomolgus GPVI Protein (GP6-CM101) Summary

Product Description

 Recombinant Cynomolgus GPVI Protein is expressed from HEK293 with His tag at the C-Terminus; It contains Gln21-Asn251.

Product Background

 The immunoglobulin receptor GPVI (glycoprotein VI) is selectively expressed on megakaryocytes and platelets and is currently recognized as a receptor for not only collagen but also a variety of plasma and vascular proteins, including fibrin, fibrinogen, laminin, fibronectin, and galectin-3.

Cynomolgus GPVI Protein (GP6-CM101) Specifications/Details

Protein
 GPVI
Synonyms
 GPVI; Gp6; Glycoprotein 6; MGC138168
Accession
Species
 Cynomolgus
Biotinylated
 no
Amino Acid Range
 Gln21-Asn251
Molecular Weight
 The protein has a predicted MW of 26.42 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Cynomolgus GPVI, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-GPVI Antibody, hFc Tag with the EC50 of 4.9 ng/ml determined by ELISA (QC Test).
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Cynomolgus GPVI, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-GPVI Antibody, hFc Tag with the EC50 of 4.9 ng/ml determined by ELISA (QC Test). Immobilized Cynomolgus GPVI, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-GPVI Antibody, hFc Tag with the EC50 of 4.9 ng/ml determined by ELISA (QC Test).
Cynomolgus GPVI on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus GPVI on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus GPVI is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus GPVI is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...