Cynomolgus IL-1 alpha/IL-1A Protein (IL1-CM01A)
Cynomolgus IL-1 alpha/IL-1A Protein (IL1-CM01A)
Cynomolgus IL-1 alpha/IL-1A Protein (IL1-CM01A)
  • Express System: HEK293
  • Product Tag: No Tag
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 10.68 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Ser113-Ala271
Catalog #IL1-CM01A
Regular price $345.00
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Product Description

Recombinant Cynomolgus IL-1 alpha/IL-1A Protein is expressed from HEK293 without tag.It contains Ser113-Ala271.

Product Background

The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.

Product Category

Recombinant Protein / Antibody discovery

Protein

IL-1 alpha/IL-1A

Synonyms

Interleukin-1 alpha; IL-1 alpha; Hematopoietin-1; IL1A; IL1F1; IL-1 ALPHA; IL1α; IL-1A; IL1

Accession

Species

Cynomolgus

Biotinylated

no

Amino Acid Range

Ser113-Ala271

Molecular Weight

The protein has a predicted MW of 18.13 kDa. Due to glycosylation, the protein migrates to 26-33 kDa based on Bis-Tris PAGE result.

Activity

The affinity constant of 10.68 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

No Tag

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human IL-1R1, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-1 alpha, No Tag with an affinity constant of 10.68 uM as determined in SPR assay (Biacore T200). Human IL-1R1, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-1 alpha, No Tag with an affinity constant of 10.68 uM as determined in SPR assay (Biacore T200).
Cynomolgus IL-1 alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus IL-1 alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus IL-1 alpha is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus IL-1 alpha is greater than 95% as determined by SEC-HPLC.

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