Name: Cynomolgus IL-1 Beta/IL-1F2 Protein (IL1-CE10B)
Brand: KactusBio
SKU: IL1-CE10B-100UG
Price: 315.0 USD
Availability: InStock

Cynomolgus IL-1 Beta/IL-1F2 Protein (IL1-CE10B)

Human IL-1 RII, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus IL-1 Beta, His Tag with an affinity constant of 1.40 nM as determined in SPR assay (Biacore T200).

Cynomolgus IL-1 Beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus IL-1 Beta is greater than 95% as determined by SEC-HPLC.

Express System: E.coli
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 1.40 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Ala117-Ser268

Catalog #IL1-CE10B

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus IL-1 Beta/IL-1F2 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Ala117-Ser268.
Product Background	Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells.
Product Category	Recombinant Protein / Antibody discovery

Protein	IL-1 Beta/IL-1F2
Synonyms	Interleukin-1 beta; IL-1 beta; IL1F2; IL1B; IL-1BETA; IL1F2; IL-1β; IL-1 beta; IL-1B ;Interleukin-1 β; IL-1 β; IL-1β; IL-1 β
Accession	A0A2K5VDC7
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Ala117-Ser268
Molecular Weight	The protein has a predicted MW of 18.33 kDa same as Bis-Tris PAGE result.
Activity	The affinity constant of 1.40 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS,100mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human IL-1 RII, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus IL-1 Beta, His Tag with an affinity constant of 1.40 nM as determined in SPR assay (Biacore T200).
	Cynomolgus IL-1 Beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus IL-1 Beta is greater than 95% as determined by SEC-HPLC.