Name: Cynomolgus IL-1 Rrp2/IL-1 R6 Protein (IL1-CM1L2)
Brand: KactusBio
SKU: IL1-CM1L2-100UG
Price: 270.0 USD
Availability: InStock

Cynomolgus IL-1 Rrp2/IL-1 R6 Protein (IL1-CM1L2)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Asp20-Arg335

Catalog #IL1-CM1L2

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus IL-1 Rrp2/IL-1 R6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp20-Arg335.
Product Background	The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.
Product Category	Recombinant Protein

Target	IL-1 Rrp2/IL-1 R6
Synonyms	IL-1 R6; IL-1 Rrp2; IL1RL2; IL1Rrp2; IL1RRP2; IL-36R
Accession	EHH61702.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Asp20-Arg335
Molecular Weight	The protein has a predicted MW of 37.1 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Cynomolgus IL-1 Rrp2/IL-1 R6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus IL-1 Rrp2/IL-1 R6 is greater than 95% as determined by SEC-HPLC.

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