• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Asp20-Arg335
Catalog #IL1-CM1L2
Price
Regular price $297.00
Regular price Sale price $297.00
/
Size
Avantor VWR Fisher Scientific

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Cynomolgus IL-1 Rrp2/IL-1 R6 Protein (IL1-CM1L2) Summary

Product Description

 Recombinant Cynomolgus IL-1 Rrp2/IL-1 R6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp20-Arg335.

Product Background

 The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.

Cynomolgus IL-1 Rrp2/IL-1 R6 Protein (IL1-CM1L2) Specifications/Details

Protein
 IL-1 Rrp2/IL-1 R6
Synonyms
 IL-1 R6; IL-1 Rrp2; IL1RL2; IL1Rrp2; IL1RRP2; IL-36R;IL1R6; IL36R
Accession
Species
 Cynomolgus
Biotinylated
 no
Amino Acid Range
 Asp20-Arg335
Molecular Weight
 The protein has a predicted MW of 37.1 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Cynomolgus IL-1 Rrp2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus IL-1 Rrp2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus IL-1 Rrp2 is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus IL-1 Rrp2 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
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