Cynomolgus IL-17F Protein (ILF-CM118)

Immobilized Cynomolgus IL-17F, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17R alpha, hFc Tag (Cat. CD7-HM2RA) with the EC50 of 0.11ug/ml determined by ELISA.

Immobilized Cynomolgus IL-17F, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag (Cat. IL1-HM2RC) with the EC50 of 15.0ng/ml determined by ELISA.

Cynomolgus IL-17F on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus IL-17F is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: N-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus IL-17F, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17R alpha, hFc Tag (Cat. CD7-HM2RA) with the EC50 of 0.11ug/ml determined by ELISA.
Amino Acid Range: Arg31-Gln163

Catalog #ILF-CM118

Price

$330⁰⁰

Size

Order by 4pm ET for delivery on:

Cynomolgus IL-17F Protein (ILF-CM118) Summary

Product Description

Recombinant Cynomolgus IL-17F Protein is expressed from HEK293 with His tag at the N-terminus.It contains Arg31-Gln163.

Product Background

The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17A through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable sequence divergence at the N‑terminus.IL-17F is ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover.

Cynomolgus IL-17F Protein (ILF-CM118) Specifications/Details

Protein	IL-17F
Synonyms	Cytokine ML-1; IL17F; IL-17F; CANDF6; IL-17F; ML1;Cytokine ML1
Accession	G7P4V0-1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Arg31-Gln163
Molecular Weight	The protein has a predicted MW of 16.05 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus IL-17F, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17R alpha, hFc Tag (Cat. CD7-HM2RA) with the EC50 of 0.11ug/ml determined by ELISA.
Product Tag	N-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 8% trehalose (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Cynomolgus IL-17F, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17R alpha, hFc Tag (Cat. CD7-HM2RA) with the EC50 of 0.11ug/ml determined by ELISA.
	Immobilized Cynomolgus IL-17F, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag (Cat. IL1-HM2RC) with the EC50 of 15.0ng/ml determined by ELISA.
	Cynomolgus IL-17F on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus IL-17F is greater than 95% as determined by SEC-HPLC.