Cynomolgus IL-18RAP Protein (IL8-CM1AP)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus IL-18RAP, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-18RAP Antibody, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Phe20-Arg356

Catalog: IL8-CM1AP

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Product Description	Recombinant Cynomolgus IL-18RAP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe20-Arg356.
Product Background	IL-18RAP, also known as IL-18Rβ or IL-1R7, is component of IL-18 receptor complex and its interactions with IL-18R1 mediate signal transduction initiated by IL-18 although it does not directly bind IL-18 in vitro.
Product Category	Recombinant Protein

Target	IL-18RAP
Gene/Protein ID	A0A2K5VDC3
Species	Cynomolgus
Exact Sequence	Phe20-Arg356
Molecular Weight	The protein has a predicted MW of 39.5 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Cynomolgus IL-18RAP, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-18RAP Antibody, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Cynomolgus IL-18RAP, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-18RAP Antibody, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA.
	The purity of Cynomolgus IL-18RAP is greater than 95% as determined by SEC-HPLC.
	Cynomolgus IL-18RAP on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.