Name: Cynomolgus IL-1R3/IL-1 RAcP Protein (ILR-CM1R3)
Brand: KactusBio
SKU: ILR-CM1R3-100UG
Price: 315.0 USD
Availability: InStock

Cynomolgus IL-1R3/IL-1 RAcP Protein (ILR-CM1R3)

Immobilized Cynomolgus IL-1R3, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-IL-1R3 Antibody, hFc Tag with the EC50 of 4.0 ng/ml determined by ELISA.

Cynomolgus IL-1R3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus IL-1R3 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Activity: Immobilized Cynomolgus IL-1R3, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-IL-1R3 Antibody, hFc Tag with the EC50 of 4.0 ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Ser21-Cys362

Catalog #ILR-CM1R3

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus IL-1R3/IL-1 RAcP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser21-Cys362.
Product Background	IL-1 Receptor Accessory Protein (IL-1 RAcP), also known as IL-1 R3, is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins. It serves as a non-ligand-binding component of the receptors for IL-1 alpha, IL-1 beta, IL-33, and IL-36. IL-1 R3 is a coreceptor for IL1RL2 in the IL-36 signaling system. IL-1 R3 is a coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
Product Category	Recombinant Protein / Antibody discovery

Protein	IL-1R3/IL-1 RAcP
Synonyms	IL1RAP; IL-1RAP; C3orf13; IL-1 R3; IL-1 RAcP
Accession	G7NYP7
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Ser21-Cys362
Molecular Weight	The protein has a predicted MW of 40.49 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus IL-1R3, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-IL-1R3 Antibody, hFc Tag with the EC50 of 4.0 ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus IL-1R3, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-IL-1R3 Antibody, hFc Tag with the EC50 of 4.0 ng/ml determined by ELISA.
	Cynomolgus IL-1R3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus IL-1R3 is greater than 95% as determined by SEC-HPLC.