Name: Cynomolgus IL-22 Protein (IL2-CM122)
Brand: KactusBio
SKU: IL2-CM122-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus IL-22, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-22R alpha 1, hFc Tag with the EC50 of 58.1ng/ml determined by ELISA (QC Test). The affinity constant of 60.21 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Ala34-Ile179

Catalog #IL2-CM122

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus IL-22 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala34-Ile179.
Product Background	The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production.
Product Category	Recombinant Protein / Antibody discovery

Protein	IL-22
Synonyms	Interleukin-22; IL-22; Cytokine Zcyto18; IL-TIF; IL-D110; TIFa; TIFIL-23; ZCYTO18
Accession	G7PHZ7
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Ala34-Ile179
Molecular Weight	The protein has a predicted MW of 17.69 kDa. Due to glycosylation, the protein migrates to 32-42 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus IL-22, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-22R alpha 1, hFc Tag with the EC50 of 58.1ng/ml determined by ELISA (QC Test). The affinity constant of 60.21 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Cynomolgus IL-22R alpha 1, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-22, His Tag with an affinity constant of 60.21 nM as determined in SPR assay (Biacore T200).
	Immobilized Cynomolgus IL-22, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-22R alpha 1, hFc Tag with the EC50 of 58.1ng/ml determined by ELISA (QC Test).
	Cynomolgus IL-22 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus IL-22 is greater than 95% as determined by SEC-HPLC.