Product Description |
Recombinant Cynomolgus IL-31 RA-Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala20-Glu519. |
Product Background |
Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex for IL-31 together with the beta subunit of oncostatin M receptor (OSMR beta). OSMR beta is expressed in a subset of small-sized nociceptive neurons of adult dorsal root ganglia (DRGs). IL-31 and OSM may thus have redundant functions in the development of OSMRbeta-expressing neurons. |
Product Category |
Recombinant Protein |
Target |
IL-31 RA |
Synonyms |
IL-31RA; IL-31R-alpha; Gp130-like receptor; CRL3; GPL; ZcytoR17; GLM-R; CRL3Glmr |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
no |
Amino Acid Range |
Ala20-Glu519 |
Molecular Weight |
The protein has a predicted MW of 58.67 kDa. Due to glycosylation, the protein migrates to 90-120 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Cynomolgus IL-31RA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>90% as determined by HPLC |
Endotoxin |
Less than 0.1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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Immobilized Cynomolgus IL-31RA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA (QC Test). |
|
|
Cynomolgus IL-31 RA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Cynomolgus IL-31 RA-Protein is greater than 90% as determined by SEC-HPLC. |
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