Cynomolgus IL-31 RA-Protein (ILR-CM1RA)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: >95% as determined by Bis-Tris PAGE;>90% as determined by HPLC
  • Activity: Immobilized Cynomolgus IL-31RA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Ala20-Glu519
Catalog #ILR-CM1RA
Regular price $315.00
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Product Description

Recombinant Cynomolgus IL-31 RA-Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala20-Glu519.

Product Background

Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex for IL-31 together with the beta subunit of oncostatin M receptor (OSMR beta). OSMR beta is expressed in a subset of small-sized nociceptive neurons of adult dorsal root ganglia (DRGs). IL-31 and OSM may thus have redundant functions in the development of OSMRbeta-expressing neurons.

Product Category

Recombinant Protein

Protein

IL-31 RA

Synonyms

IL-31RA; IL-31R-alpha; Gp130-like receptor; CRL3; GPL; ZcytoR17; GLM-R; CRL3Glmr

Accession

Species

Cynomolgus

Biotinylated

no

Amino Acid Range

Ala20-Glu519

Molecular Weight

The protein has a predicted MW of 58.67 kDa. Due to glycosylation, the protein migrates to 90-120 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Cynomolgus IL-31RA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

>95% as determined by Bis-Tris PAGE;>90% as determined by HPLC

Endotoxin

Less than 0.1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Cynomolgus IL-31RA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA (QC Test). Immobilized Cynomolgus IL-31RA, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA (QC Test).
Cynomolgus IL-31 RA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus IL-31 RA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus IL-31 RA-Protein is greater than 90% as determined by SEC-HPLC. The purity of Cynomolgus IL-31 RA-Protein is greater than 90% as determined by SEC-HPLC.

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