Name: Cynomolgus IL-4 R alpha/CD124 Protein (ILA-CM14R)
Brand: KactusBio
SKU: ILA-CM14R-100UG
Price: 315.0 USD
Availability: InStock

Cynomolgus IL-4 R alpha/CD124 Protein (ILA-CM14R)

Cynomolgus IL-4, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-4 R alpha, His Tag with an affinity constant of 13.48 nM as determined in SPR assay (Biacore T200).

Immobilized Human IL-4, No Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Cynomolgus IL-4 R alpha, His Tag with the EC50 of 97.8 ng/ml determined by ELISA (QC Test).

Cynomolgus IL-4 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus IL-4 R alpha is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Activity: Immobilized Human IL-4, No Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Cynomolgus IL-4 R alpha, His Tag with the EC50 of 97.8 ng/ml determined by ELISA (QC Test). The affinity constant of 13.48 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Met26-Arg232

Catalog #ILA-CM14R

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus IL-4 R alpha/CD124 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Met26-Arg232.
Product Background	Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family. The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells.
Product Category	Recombinant Protein / Antibody discovery

Protein	IL-4 R alpha/CD124
Synonyms	CD124; IL-4 R alpha; IL-4R subunit alpha; IL4R; IL-4Ra; IL4RACD124
Accession	G7Q0S7
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Met26-Arg232
Molecular Weight	The protein has a predicted MW of 24.84 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-4, No Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Cynomolgus IL-4 R alpha, His Tag with the EC50 of 97.8 ng/ml determined by ELISA (QC Test). The affinity constant of 13.48 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Cynomolgus IL-4, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-4 R alpha, His Tag with an affinity constant of 13.48 nM as determined in SPR assay (Biacore T200).
	Immobilized Human IL-4, No Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Cynomolgus IL-4 R alpha, His Tag with the EC50 of 97.8 ng/ml determined by ELISA (QC Test).
	Cynomolgus IL-4 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus IL-4 R alpha is greater than 95% as determined by SEC-HPLC.