Name: Cynomolgus IL-6 Protein (IL6-CM001)
Brand: KactusBio
SKU: IL6-CM001-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus IL-6, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-6 R alpha, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Ala28-Met212

Catalog #IL6-CM001

Size

100UG

500UG

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Cynomolgus IL-6 Protein (IL6-CM001) Summary

Product Description	Recombinant Cynomolgus IL-6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala28-Met212.
Product Background	IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Cynomolgus IL-6 Protein (IL6-CM001) Specifications/Details

Protein	IL-6
Synonyms	IFN-beta-2; IL6; IL-6; BSF-2; CDF; MGI-2A; Interleukin-6; HSF; IFNB2; HGF;IFN-β-2
Accession	P79341
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Ala28-Met212
Molecular Weight	The protein has a predicted MW of 22.06 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus IL-6, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-6 R alpha, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus IL-6, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IL-6 R alpha, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA.
	Cynomolgus IL-6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Human IL-6 R alpha, hFc Tag on ProA-Biosensor can bind Cynomolgus IL-6, His Tag with an affinity constant of 21.60 nM as determined in BLI assay (Gator® Prime).
	The purity of Cynomolgus IL-6 is greater than 95% as determined by SEC-HPLC.