Name: Cynomolgus Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-CM1AB)
Brand: KactusBio
SKU: ITG-CM1AB-100UG
Price: 375.0 USD
Availability: InStock

Cynomolgus Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-CM1AB)

Cynomolgus ITGA2&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus ITGA2&ITGB1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Tyr30-Pro1130(ITGA2) acidic tail & Gln161-Asp868(ITGB1) basic tail

Catalog #ITG-CM1AB

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-terminus.It contains Tyr30-Pro1130 (ITGA2) acidic tail and Gln161-Asp868 (ITGB1) basic tail.
Product Background	The α2β1 integrin, also known as VLA-2, GPIa-IIa, CD49b, was first identified as an extracellular matrix receptor for collagens and/or laminins. It is now recognized that the α2β1 integrin serves as a receptor for many matrix and nonmatrix molecules. It plays a critical role in platelet function and homeostasis.
Product Category	Recombinant Protein / Antibody discovery

Protein	Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer
Synonyms	α2β1; Integrin alpha A1 beta 1; alpha A1 beta 1; alpha A1; beta 1; ITGA1&ITGB1; ITGA&ITGB; VLA-2, GPIa-IIa, CD49b;Integrin alpha A1 β 1; alpha A1 β 1; β 1
Accession	G8F2Z5(ITGA2)&A0A7N9D0D7(ITGB1)
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Tyr30-Pro1130(ITGA2) acidic tail & Gln161-Asp868(ITGB1) basic tail
Molecular Weight	The protein has a predicted MW of 126.69 kDa (ITGA2) and 83.16 kDa (ITGB1). Due to glycosylation, the protein migrates to 130-170 kDa (ITGA2) and 100-130 kDa (ITGB1) based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Cynomolgus ITGA2&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus ITGA2&ITGB1 is greater than 95% as determined by SEC-HPLC.