Cynomolgus Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-CM1AB)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Tyr30-Pro1130(ITGA2) acidic tail & Gln161-Asp868(ITGB1) basic tail

Catalog: ITG-CM1AB

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Product Description Recombinant Cynomolgus Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-terminus.It contains Tyr30-Pro1130 (ITGA2) acidic tail and Gln161-Asp868 (ITGB1) basic tail.

Product Background

The α2β1 integrin, also known as VLA-2, GPIa-IIa, CD49b, was first identified as an extracellular matrix receptor for collagens and/or laminins. It is now recognized that the α2β1 integrin serves as a receptor for many matrix and nonmatrix molecules. It plays a critical role in platelet function and homeostasis.

Product Category

Recombinant Protein

Target

Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer
Accession

Species

Cynomolgus

Amino Acid Range

Tyr30-Pro1130(ITGA2) acidic tail & Gln161-Asp868(ITGB1) basic tail
Molecular Weight The protein has a predicted MW of 126.69 kDa (ITGA2) and 83.16 kDa (ITGB1). Due to glycosylation, the protein migrates to 130-170 kDa (ITGA2) and 100-130 kDa (ITGB1) based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Cynomolgus ITGA2&ITGB1 is greater than 95% as determined by SEC-HPLC.
Cynomolgus ITGA2&ITGB1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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