Name: Cynomolgus Kremen-2 Protein (KRE-CM102)
Brand: KactusBio
SKU: KRE-CM102-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus Kremen-2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kremen-2 Antibody, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gly26-Ala364

Catalog #KRE-CM102

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus Kremen-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly26-Ala364.
Product Background	Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Compared to para-cancerous tissues, Krm2 was significantly up-regulated in gastric cancer tissues and was positively correlated with the pathological grade of gastric cancer patients. Krm2 can be a potent candidate for designing of targeted therapy.
Product Category	Recombinant Protein / Antibody discovery

Protein	Kremen-2
Synonyms	KRM2; KREMEN2; Kremen-2; Dickkopf receptor 2
Accession	XP_005591068.2
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gly26-Ala364
Molecular Weight	The protein has a predicted MW of 37.04 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus Kremen-2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kremen-2 Antibody, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus Kremen-2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Kremen-2 Antibody, hFc Tag with the EC50 of 4.8ng/ml determined by ELISA.
	Cynomolgus Kremen-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus Kremen-2 is greater than 95% as determined by SEC-HPLC.