Name: Cynomolgus Latent GDF-8 Protein (GDF-CM108)
Brand: KactusBio
SKU: GDF-CM108-100UG
Price: 363.0 USD
Availability: InStock

Cynomolgus Latent GDF-8 Protein (GDF-CM108)

Immobilized Cynomolgus Latent GDF-8, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GDF8 Antibody, hFc Tag with the EC50 of 12.4ng/ml determined by ELISA.

Immobilized Cynomolgus Latent GDF-8, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 28.2ng/ml determined by ELISA.

Cynomolgus Latent GDF-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus Latent GDF-8 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: N-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus Latent GDF-8, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GDF8 Antibody, hFc Tag with the EC50 of 12.4ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gly19-Ser375

Catalog #GDF-CM108

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus Latent GDF-8 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Gly19-Ser375.
Product Background	Growth/differentiation factor 8 (GDF8), or myostatin, negatively regulates muscle mass. GDF8 is held in a latent state through interactions with its N-terminal prodomain. GDF8, like numerous TGF-β family members, is a disulfidelinked dimer that is synthesized as a precursor protein which requires cleavage by a furin-like protease to yield an N-terminal prodomain and a C-terminal mature, signaling domain.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	GDF-8
Synonyms	Myostatin; GDF8; Latent GDF8; Mstn
Accession	Q95J86
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gly19-Ser375
Molecular Weight	The protein has a predicted MW of 41.64 kDa. Due to glycosylation, the protein migrates to 13-15 kDa, 38-41 kDa and 48-52 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus Latent GDF-8, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GDF8 Antibody, hFc Tag with the EC50 of 12.4ng/ml determined by ELISA. See testing image for detail.
Product Tag	N-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus Latent GDF-8, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GDF8 Antibody, hFc Tag with the EC50 of 12.4ng/ml determined by ELISA.
	Immobilized Cynomolgus Latent GDF-8, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 28.2ng/ml determined by ELISA.
	Cynomolgus Latent GDF-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus Latent GDF-8 is greater than 95% as determined by SEC-HPLC.