Name: Cynomolgus LILRB4/CD85k/ILT3 Protein (LIL-CM1B4)
Brand: KactusBio
SKU: LIL-CM1B4-100UG
Price: 346.5 USD
Availability: InStock

Cynomolgus LILRB4/CD85k/ILT3 Protein (LIL-CM1B4)

Immobilized Cynomolgus LILRB4, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-LILRB4 Antibody, hFc Tag with the EC50 of 16.7ng/ml determined by ELISA.

Cynomolgus LILRB4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus LILRB4 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus LILRB4, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-LILRB4 Antibody, hFc Tag with the EC50 of 16.7ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gln22-Glu259

Catalog #LIL-CM1B4

Size

100UG

500UG

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Cynomolgus LILRB4/CD85k/ILT3 Protein (LIL-CM1B4) Summary

Product Description	Recombinant Cynomolgus LILRB4/CD85k/ILT3 Protein Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln22-Glu259.
Product Background	LILRB4,also known as CD85k and LIR-5, ILT3,- is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Cynomolgus LILRB4/CD85k/ILT3 Protein (LIL-CM1B4) Specifications/Details

Protein	LILRB4/CD85k/ILT3
Synonyms	HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Accession	XP_015297198.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gln22-Glu259
Molecular Weight	The protein has a predicted MW of 27.2 kDa. Due to glycosylation, the protein migrates to 35-42 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus LILRB4, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-LILRB4 Antibody, hFc Tag with the EC50 of 16.7ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus LILRB4, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-LILRB4 Antibody, hFc Tag with the EC50 of 16.7ng/ml determined by ELISA.
	Cynomolgus LILRB4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus LILRB4 is greater than 95% as determined by SEC-HPLC.