Cynomolgus LRIG1 Protein (LRI-CM101)
Cynomolgus LRIG1 Protein (LRI-CM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Cynomolgus LRIG1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LRIG1 Antibody, hFc Tag with the EC50 of 11.6ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Ala34-Thr792
Catalog #LRI-CM101
Regular price $315.00
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Product Description

Recombinant Cynomolgus LRIG1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala34-Thr792.

Product Background

The leucine-rich repeats and immunoglobulin-like domains (LRIG)-1 is a tumor suppressor gene that belongs to the LRIG family. LRIG1 expression has prognostic significance in various human cancers. Somatic mutations, which are associated with a certain rate of response to targeted therapies, are ubiquitously found in human non-small cell lung cancer (NSCLC). LRIG1 was an independent prognostic factor for OS of NSCLC patients. LRIG1 in combination with other clinicopathological risk factors was a stronger prognostic model than clinicopathological risk factors alone.

Product Category

Recombinant Protein / Antibody discovery

Protein

LRIG1

Synonyms

LIG-1; LIG1; LRIG1; D6Bwg0781e; Img

Accession

Species

Cynomolgus

Biotinylated

no

Amino Acid Range

Ala34-Thr792

Molecular Weight

The protein has a predicted MW of 84.16 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Cynomolgus LRIG1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LRIG1 Antibody, hFc Tag with the EC50 of 11.6ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Cynomolgus LRIG1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LRIG1 Antibody, hFc Tag with the EC50 of 11.6ng/ml determined by ELISA. Immobilized Cynomolgus LRIG1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-LRIG1 Antibody, hFc Tag with the EC50 of 11.6ng/ml determined by ELISA.
Cynomolgus LRIG1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus LRIG1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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