Name: Cynomolgus LY6G6D-Protein (LYD-CM16D)
Brand: KactusBio
SKU: LYD-CM16D-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: N-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Cynomolgus LY6G6D, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Asn20-Ser104

Catalog #LYD-CM16D

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus LY6G6D-Protein is expressed from HEK293 with His tag at the N-terminus.It contains Asn20-Ser104.
Product Background	LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy.
Product Category	Recombinant Protein / Antibody discovery

Protein	LY6G6D
Synonyms	Protein Ly6-D; C6orf23; G6D; MEGT1; NG25
Accession	XP_014991478.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Asn20-Ser104
Molecular Weight	The protein has a predicted MW of 10.22 kDa. Due to glycosylation, the protein migrates to 14-24 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus LY6G6D, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA. See testing image for detail.
Product Tag	N-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus LY6G6D, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA.
	Cynomolgus LY6G6D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.