Cynomolgus LY6G6D-Protein (LYD-CM16D)
Catalog: LYD-CM16D
Order now get it on
Product Description | Recombinant Cynomolgus LY6G6D-Protein is expressed from HEK293 with His tag at the N-terminus.It contains Asn20-Ser104. |
Product Background |
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy. |
Product Category |
Recombinant Protein |
Target |
LY6G6D |
Gene/Protein ID |
XP_045246087.1 |
Species |
Cynomolgus |
Exact Sequence |
Asn20-Ser104 |
Molecular Weight | The protein has a predicted MW of 10.22 kDa. Due to glycosylation, the protein migrates to 14-24 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Cynomolgus LY6G6D, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
N-His |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Lyophilized |
Shipping | Shipped at ambient temperature. |
Formulation | Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
You may also be interested in
View more associated products