Cynomolgus LY6G6D Protein (LYD-CM26D)
  • Express System: HEK293
  • Product Tag: N-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus LY6G6D, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LY6G6D Antibody, hFc Tag with the EC50 of 12.2ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Asn20-Ser104
Catalog #LYD-CM26D
Regular price $300.00
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Product Description
Recombinant Cynomolgus LY6G6D Protein is expressed from HEK293 with hFc tag at the N-terminus.It contains Asn20-Ser104.
Product Background
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy.
Product Category
Recombinant Protein
Target
LY6G6D
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Asn20-Ser104
Molecular Weight
The protein has a predicted MW of 34.65 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Cynomolgus LY6G6D, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LY6G6D Antibody, hFc Tag with the EC50 of 12.2ng/ml determined by ELISA. See testing image for detail.
Product Tag
N-hFc
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Cynomolgus LY6G6D, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-LY6G6D Antibody, hFc Tag with the EC50 of 12.2ng/ml determined by ELISA.
Cynomolgus LY6G6D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus LY6G6D is greater than 95% as determined by SEC-HPLC.

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