Name: Cynomolgus MASP2 Protein (MSP-CE102)
Brand: KactusBio
SKU: MSP-CE102-100UG
Price: 445.5 USD
Availability: InStock

Express System: E.coli
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: Immobilized Cynomolgus MASP2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Narsoplimab, hFc Tag with the EC50 of 11.9ng/ml determined by ELISA.
Amino Acid Range: Thr287-Phe686

Catalog #MSP-CE102

Size

100UG

500UG

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Cynomolgus MASP2 Protein (MSP-CE102) Summary

Product Description	Recombinant Cynomolgus MASP2 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Thr287-Phe686.
Product Background	Te MASP2 gene is located on the chromosome 1p36.23–31 and encodes two proteins, MASP-2 and Map198. Both the levels and function of MASP-2 are modulated by the single-nucleotide polymorphisms (SNPs) of the MASP2 gene. Te level of MASP-2 in plasma plays a dual role in the infection and progression of infectious diseases. Te defciency of MASP-2 in plasma has been associated with the susceptibility of HIV. By contrast, the overproduction of MASP-2 may increase the infammatory efect.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery/Others

Cynomolgus MASP2 Protein (MSP-CE102) Specifications/Details

Protein	MASP2
Synonyms	MAP19; MASP-2; MASP1P1; sMap
Accession	A0A2K5UJY0
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Thr287-Phe686
Molecular Weight	The protein has a predicted MW of 46.8 kDa. Due to autocatalytic cleavage, the protein migrates to 21-24 kDa&28-30 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus MASP2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Narsoplimab, hFc Tag with the EC50 of 11.9ng/ml determined by ELISA.
Product Tag	C-His
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in 50mM Tris, 200mM NaCl (pH 9.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus MASP2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Narsoplimab, hFc Tag with the EC50 of 11.9ng/ml determined by ELISA.
	Cynomolgus MASP2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Cynomolgus MASP2 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.
	Loaded Narsoplimab on ProA-Biosensor can bind Cynomolgus MASP2, His Tag with an affinity constant of 7.93 nM as determined in BLI assay (Gator® Prime).