Cynomolgus MSLN/Mesothelin Protein (MSL-CM1D1)

Immobilized Cynomolgus MSLN, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-MSLN Antibody, hFc Tag with the EC50 of 7.9ng/ml determined by ELISA.

Cynomolgus MSLN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus MSLN is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus MSLN, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-MSLN Antibody, hFc Tag with the EC50 of 7.9ng/ml determined by ELISA.
Amino Acid Range: Met487-Gly580

Catalog #MSL-CM1D1

Price

$330⁰⁰

Size

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Cynomolgus MSLN/Mesothelin Protein (MSL-CM1D1) Summary

Product Description

Recombinant Cynomolgus MSLN/Mesothelin Protein is expressed from HEK293 with His tag at the C-terminus.It contains Met487-Gly580.

Product Background

Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.A knockout mouse line that lacks mesothelin reproduces and develops normally.

Cynomolgus MSLN/Mesothelin Protein (MSL-CM1D1) Specifications/Details

Protein	MSLN/Mesothelin
Synonyms	MSLN; CAK1 antigen; CAK1; Mesothelin; MPF; MPFSMRP; SMR;
Accession	XP_005590873.4
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Met487-Gly580
Molecular Weight	The protein has a predicted MW of 12.08 kDa. Due to glycosylation, the protein migrates to 15-25 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus MSLN, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-MSLN Antibody, hFc Tag with the EC50 of 7.9ng/ml determined by ELISA.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Cynomolgus MSLN, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-MSLN Antibody, hFc Tag with the EC50 of 7.9ng/ml determined by ELISA.
	Cynomolgus MSLN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus MSLN is greater than 95% as determined by SEC-HPLC.