Name: Cynomolgus MSLN/Mesothelin Protein, Ultra Low Endotoxin (MSL-CM281-UL)
Brand: KactusBio
SKU: MSL-CM281-UL-100UG
Price: 381.0 USD
Availability: InStock

Cynomolgus MSLN/Mesothelin Protein, Ultra Low Endotoxin (MSL-CM281-UL)

Immobilized Cynomolgus MSLN, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human CA125, His Tag with the EC50 of 0.12ug/ml determined by ELISA.

Immobilized Cynomolgus MSLN, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-MSLN Antibody, hFc Tag with the EC50 of 2.8ng/ml determined by ELISA.

Cynomolgus MSLN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus MSLN is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus MSLN, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human CA125, His Tag with the EC50 of 0.12ug/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Asp296-Ser598

Catalog #MSL-CM281-UL

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus MSLN/Mesothelin Protein is expressed from HEK293 with His tag at the C-terminus.It contains Asp296-Ser598.
Product Background	Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.A knockout mouse line that lacks mesothelin reproduces and develops normally.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Protein	MSLN/Mesothelin
Synonyms	MSLN; CAK1 antigen; CAK1; Mesothelin; MPF; MPFSMRP; SMR;
Accession	XP_005590873.3
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Asp296-Ser598
Molecular Weight	The protein has a predicted MW of 34.87 kDa. Due to glycosylation, the protein migrates to 43-53 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus MSLN, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human CA125, His Tag with the EC50 of 0.12ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.01 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus MSLN, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human CA125, His Tag with the EC50 of 0.12ug/ml determined by ELISA.
	Immobilized Cynomolgus MSLN, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-MSLN Antibody, hFc Tag with the EC50 of 2.8ng/ml determined by ELISA.
	Cynomolgus MSLN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus MSLN is greater than 95% as determined by SEC-HPLC.